的新药研发也屡屡失败，因此，重视预防对AD 意义深远。近些年随着AD 诊断生物标记物的迅速发展，
AD 的早期诊断变得越来越准确。此外，越来越多的证据显示AD 和其他慢性病一样，有许多可防可控
Prevention of Alzheimer disease： from risk factors to early diagnosis
Li Yuxia， Yu Jintai， Zhao Mingyan，
Alzheimer disease（ AD） is the main cause of dementia. At present， there is no effective
treatment plan. The development of new drugs for AD treatment has also been persistently unsuccessful.
Therefore， it is of great significance to emphasize AD prevention. In recent years， with the rapid development
of biomarkers for the diagnosis of AD， early diagnosis of AD has become increasingly accurate. In addition，
there is growing evidence that AD， like other chronic diseases， has many preventable risk factors， and early
intervention with these risk factors can help delay or prevent AD. This article mainly discusses the risk factors
and pathogenic mechanism of AD， from primary prevention based on identifying and reducing risk factors， to
secondary prevention based on early detection of AD pathophysiological characteristics， early diagnosis in the
early preclinical stage， and early intervention. The aim of this article is to call for awareness and attention to AD
prevention and promote scientific prevention and control.