难治性抑郁症患者甲状腺激素水平的分析
引用本文:
印海翔,钮伟芳.难治性抑郁症患者甲状腺激素水平的分析[J].神经疾病与精神卫生,2007,7(3):178-179.
作者姓名:
作者单位:
1. 200030,上海精神卫生中心
2. 河北省荣军医院
摘    要:
目的 探讨难治性抑郁症患者的甲状腺激素水平。方法 按性别、年龄1:1匹配选取难治性抑郁症患者和健康对照各30例,采用放射免疫法测定患者组治疗前和对照组血清TSH、T3、T4、FT3、FT4水平。结果 患者组异常者17例,占56.7%,对照组异常者2例,占6.7%,两组比较,患者组甲状腺激素水平出现异常的比率明显高于对照组,主要表现为TSH升高、T3降低、FT4降低,差异均有统计学意义(P〈0.05)。结论 难治性抑郁症患者中有56.7%的患者存在亚临床型甲状腺功能的减退。

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文章编号:
1009-6574(2007)03-0178-02
修稿时间:
2007-03-20

Investigation on the serum Level of thyroid hormones in patients with treatment- resistant depression
YIN Hai-xiang,NIU Wei-fang.Investigation on the serum Level of thyroid hormones in patients with treatment- resistant depression[J].Nervous Diseases and Mental Health,2007,7(3):178-179.
Authors:
Affiliation:
Shanghai Mental Health Center, Shanghai 200030, China
Abstract:
Objective To examine the thyroid hormones level of in patients serum with treatment-resistant depression(TRD).Methods 30 patients with TRD were measured for serum thyroxine stimulating hormone(TSH),total triiodothyronine(T3),total thyroxine(T4),free triiodothyronine(FT3) and free thyroxine(FT4) by Radio-immunity before treatment.Simultaneously,30 normal subjects matched in sex and age were recruited as controls.Results There were 17(56.7%) patients whose serum thyroid hormones level was abnormal which represent as TSH up regulation,T3 and T4 down regulation,and there were only 2(6.7%) abnormal in the controls.There were significant differences between the two groups(P<0.05).Conclusions There was sub-clinical thyroid function impairment in 56.7% treatment-resistant depression patients.
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